While less discussed, cannabidiolic acid (CBDA) offers diverse health advantages. Preliminary studies indicate its potential in treating anxiety, inflammation, seizures, and specific cancer types.
Despite limited research, scientists believe CBDA could offer a safer alternative to drugs with adverse long-term effects. Let’s delve into CBDA’s properties, functions, and the therapeutic benefits it potentially offers.
What is CBDA?
CBDA, or cannabidiolic acid, is naturally present in most cannabis plants in small quantities. Being non-intoxicating, it’s legal in nearly all states.
CBDA boasts higher bioavailability, making it more easily absorbed by the body (up to 11 times better) when orally consumed compared to CBD.
Studies on animals indicate that CBDA’s potency surpasses that of CBD due to its more effective interaction with the body, potentially addressing various health concerns.
How CBDA Works
Unlike cannabinoids binding directly to CB1 and CB2 receptors, CBDA interacts by inhibiting cyclooxygenase-2 (COX-2) enzymes linked to inflammation resulting from infections or injuries. By blocking COX-2 enzymes, CBDA can alleviate inflammation and pain.
Additionally, studies on rodents demonstrate CBDA’s influence on serotonin levels, a chemical crucial for basic human functions like mood regulation, digestion, and nausea control.
Anti-Inflammation
CBDA, observed as a selective COX-2 inhibitor, showcases anti-inflammatory properties in cell culture research. Unlike traditional NSAIDs, CBDA can potentially mitigate inflammation without causing significant gastrointestinal harm.
Anti-Nausea
Through its interaction with the 5-HT1A receptor, CBDA displays superiority over CBD in reducing nausea and vomiting, even at significantly smaller doses.
It’s a potential remedy for anticipatory nausea experienced by cancer patients before chemotherapy, an area lacking effective medication.
Anti-Cancer
Studies indicate CBDA’s ability to hinder the growth and migration of specific breast cancer cells. It decreases the efficacy of proteins boosting cancer cell growth, while enhancing others that suppress cancer spread.
Anti-Anxiety
CBDA’s potential as an antidepressant at significantly lower doses than CBD makes it a promising option for anxiety treatment.
Anti-Seizures
Preliminary data suggests CBDA’s bioavailability and swift action might surpass CBD’s, making it effective in preventing seizures with smaller doses and potentially fewer side effects.
Improves Cardiovascular Health
Research reveals phytocannabinoids like CBDA positively impact cardiovascular health by managing heart-related conditions.
Where to Find Quality CBDA Products
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While research has mainly centred on animal models, further clinical trials on humans are necessary to validate CBDA’s effectiveness.
Initial studies, however, paint a promising picture for CBDA in addressing diverse health issues effectively and safely.